diff --git a/packages/react-reconciler/src/ReactFiberHooks.js b/packages/react-reconciler/src/ReactFiberHooks.js
index f72056f674..abe1516520 100644
--- a/packages/react-reconciler/src/ReactFiberHooks.js
+++ b/packages/react-reconciler/src/ReactFiberHooks.js
@@ -1226,7 +1226,7 @@ function useMemoCache(size: number): Array<any> {
   updateQueue.memoCache = memoCache;
 
   let data = memoCache.data[memoCache.index];
-  if (data === undefined) {
+  if (data === undefined || (__DEV__ && ignorePreviousDependencies)) {
     data = memoCache.data[memoCache.index] = new Array(size);
     for (let i = 0; i < size; i++) {
       data[i] = REACT_MEMO_CACHE_SENTINEL;
diff --git a/packages/react-refresh/src/__tests__/ReactFreshIntegration-test.js b/packages/react-refresh/src/__tests__/ReactFreshIntegration-test.js
index 2115a15f67..cc9deb6236 100644
--- a/packages/react-refresh/src/__tests__/ReactFreshIntegration-test.js
+++ b/packages/react-refresh/src/__tests__/ReactFreshIntegration-test.js
@@ -1637,8 +1637,7 @@ describe('ReactFreshIntegration', () => {
       }
     });
 
-    // eslint-disable-next-line jest/no-disabled-tests
-    it.skip('resets useMemoCache cache slots', async () => {
+    it('resets useMemoCache cache slots', async () => {
       if (__DEV__) {
         await render(`
           const useMemoCache = require('react/compiler-runtime').c;